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Open Access Software

IMGT/Collier-de-Perles: a two-dimensional visualization tool for amino acid domain sequences

Dimitrios Vlachakis12, Christos Feidakis1, Vasileios Megalooikonomou2 and Sophia Kossida1*

Author Affiliations

1 Bioinformatics & Medical Informatics Team, Biomedical Research Foundation, Academy of Athens, Soranou Efessiou 4, Athens, 11527, Greece

2 Computer Engineering and Informatics Department, School of Engineering University of Patras, Patras, 26500, Greece

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Theoretical Biology and Medical Modelling 2013, 10:14  doi:10.1186/1742-4682-10-14

Published: 21 February 2013

Abstract

IMGT/Collier-de-Perles is a tool that allows the user to analyze and draw two-dimensional graphical representations (or IMGT Collier de Perles) of protein domains (e.g., hydropathy plots). The IMGT/Collier-de-Perles specializes in the area of immunoglobulins (IG) or antibodies, T cell receptors (TR) and major histocompatibility (MH) of human and other vertebrate species as well as other proteins of the immunoglobulin superfamily (IgSF) and of the major histocompatibility superfamily (MhSF) and related proteins of the immune system of vertebrates and invertebrates.

Keywords:
IMGT/Collier-de-Perles; IMGT Collier de Perles; Graphical representation; Protein domains