|
The genes of the (+)-training set (without orthologs). Marked with asterisks are those included in the "seed" set. |
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| No |
Gene name |
Accessin no. And LocusLinkID |
Experimental evidence |
Additional information |
Participation in anti-Pseudomonas response |
|
|
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| 1 |
Monocyte chemoattractant protein-1, MCP-1* |
EMBL: D26087 |
Microarray [66], other experiments [20,21,38] |
Is well know as expressed in antibacterial response |
100% |
| 2 |
β-defensin* |
LocusLinkID: 1673 |
[15,18,19,39,40] |
Is well known as expressed in antibacterial response; important target gene in innate immunity |
100% |
| 3 |
Interferon regulatory factor 1, IRF-1* |
LocusLinkID: 3659 |
Microarray [66] |
Known to be expressed in epithelial cells |
probable |
| 4 |
Equilibrate nucleoside transporter 1, SLC29a1 |
LocusLinkID: 2030 |
Microarray [66] |
||
| 5 |
Proteinkinase C η type, PKCη* |
LocusLinkID: 5583 |
Microarray [66] TRANSPATH® |
Important link in Ca2+-connected pathways |
probable |
| 6 |
Folypolyglutamate synthase, FPGS |
Ensembl : ENSG00000136877 |
Microarray [66] |
||
| 7 |
RhoB* |
LocusLinkID: 388 |
Microarray [66] |
is induced as part of the immediate early response in different systems |
probable |
| 8 |
Origin recognition complex subunit 2, hORC2L |
LocusLinkID: 4999 |
Microarray [66] |
||
| 9 |
Transcription factor TEL2* |
LocusLinkID: 51513 |
Microarray [66] |
Transcription factor |
probable |
| 10 |
Interleukin 8, IL8* |
EPD: EP73083LocusLinkID: 3576 |
[10,11,26,44,45] |
Is well know as expressed in antibacterial response |
100% |
| 11 |
Transcription factor ELF3* |
LocusLinkID: 1999 |
Microarray [66] |
Transcription factor |
probable |
| 12 |
Mucin 1(mouse gene), MUC1* |
RefSeq: NM_013605 |
[17,27,28,36,47] |
Different mucins are shown as expressed in antibacterial response |
100% |
| 13 |
NF-kappaB inhibitor alpha, IkBa* |
LocusLinkID: 4792 EPD: EP73215 |
Microarray [66] |
NF-kB inhibitor, the main link in NF-kB-targeting pathways |
Very high |
| 14 |
Tissue Factor Pathway Inhibitor 2, TFPI |
LocusLinkID: 7980 EPD: EP73430 |
Microarray [66] |
||
| 15 |
Urokinase-type plasminogen activator precursor, PLAU |
LocusLinkID: 5328 |
Microarray [66] |
||
| 16 |
c-jun* |
Microarray [66] |
Transcription factor |
probable |
|
| 17 |
Cytochrom P450 dioxin-inducible* |
LocusLinkID: 1545 |
Microarray [66] |
Stress-inducible |
probable |
| 18 |
Dyphtheria toxin resistance protein, DPH2L2 |
EPD: EP74285 |
Microarray [66] |
||
Shelest and Wingender Theoretical Biology and Medical Modelling 2005 2:2 doi:10.1186/1742-4682-2-2 |
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