Figure 5.

Effect of mRNA and protein half-lives and induction time on the appearance of protein expression histograms. (A) Top: number of cells that are transcriptionally active (blank bar) and inactive (solid bar) at different induction time points under inducing condition of [TA] = 36; Bottom: number of cells that have yet to be induced (blank bar) and those that have been induced (solid bar). (B) Corresponding protein expression histograms (B shares the same time line with A), simulated with different RNA and protein half-lives. Top: = 10 min, = 20 min; Middle: = 1 h, = 2 h; Bottom: = 8 h, = 16 h. AU: arbitrary unit.