Table 4

Comparison of the results from our approach and those from Hu's using different R thresholds when normal cerebellum samples are compared with medulloblastomas

R used
Number of Genes Found in Hu's Approach
Number of Overlap Between Hu's and Our 577 Genes
Percentage of the overlapping genes based on number of genes found in Hu's method
Percentage of the overlapping genes based on our 577 selected genes

4
324
69
21%
11.9%
6
103
28
27%
4.9%
8
53
14
26%
2.4%
10
31
7
23%
1.2%

Genes found in Hu's methods using different R thresholds are compared to each other. Larger R value represents more stringent selection criterion. Genes found using smaller R values always include those found using larger R values, i.e. gene list of 324 genes contains gene list of 103 genes, etc. Genes obtained from Hu's method are also compared with 577 genes from our approach. Numbers of overlapping genes are presented in the third column for different R values. Similarly, overlapping genes for the smaller R values contains those for the larger R values, i.e. gene list of 69 genes contains gene list of 28 genes, etc.

Fan et al. Theoretical Biology and Medical Modelling 2006 3:19   doi:10.1186/1742-4682-3-19