|
The four category model: risks and cases for a population of size N. |
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| Category |
Risk of being in category |
Number of people in category |
Number of cases in category |
|
|
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| ge (high-risk genotype/high-risk exposure) |
Rge |
γεN |
γε RgeN |
| go (high-risk genotype/low-risk exposure) |
Rgo |
γ (1-ε)N |
γ (1-ε)RgoN |
| oe (low-risk genotype/high-risk exposure) |
Roe |
ε (1-γ)N |
ε (1-γ)RoeN |
| oo (low-risk genotype/low-risk exposure) |
Roo |
(1-ε) (1-γ)N |
(1-ε) (1-γ)RooN |
|
|
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| Total |
N |
rtN |
|
Wallace Theoretical Biology and Medical Modelling 2006 3:35 doi:10.1186/1742-4682-3-35 |
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