Table 3
|
Table of parameters Table of numerical parameters used for simulations. |
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| Model parameters |
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|
|
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| Parameter |
Description |
Unit |
Value |
Reference |
|
|
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 |
Duration of G1 phase |
h |
20 |
[35,44] |
| TS |
Duration of S phase |
h |
10 |
[35,44] |
 |
Duration of G2M phase |
h |
3 |
[35,44] |
 |
Duration of G0 phase |
h |
5 |
Estimated |
| TApoptosis |
Duration of the apoptotic phase |
h |
5 |
Estimated |
| Cmax |
Oxygen in blood |
mlO2 |
10-2 |
Estimated |
| αφ |
Oxygen consumption in phase φ |
mlO2s-1 |
5 – 10 × 10-15 |
Estimated |
| Tho |
Hypoxia threshold |
cell-1 |
5 × 10-15 |
Estimated |
| Tht |
Overpopulation threshold |
cell |
2000 |
Estimated |
| Rφ |
Cell Radio-sensitivity in phase φ |
Gy-1 |
0.2 – 2 |
[41-43] |
| k |
Media permeability |
m2 |
0.2 |
Estimated |
Ribba et al. Theoretical Biology and Medical Modelling 2006 3:7 doi:10.1186/1742-4682-3-7 |
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