Table 2

Kinetic parameters. Concentrations and the Michaelis-Menten constants (K₄, K₈, and K₁₁-K₁₉) are given in [nM]. First- and second-order rate constants are given in [s^-1] and [nM^-1·s^-1], respectively. V₄, V₈, and V₁₁-V₁₉are expressed in [nM·s^-1].
Reaction number	Equation	Kinetic parameter		Reference

v₁	k₁·X₁·X₂- k_-1·X₃	k₁= 0.003	k_-1= 0.06	[11]
v₂	k₂·X₃·X₃- k_-2·X₄	k₂= 0.01	k_-2= 0.1	[11]
v₃	k₃·X₄- k_-3·X₅	k₃= 1	k_-3= 0.01	[11]
v₄	V₄·X₅/(K₄+ X₅)	V₄= 450	K₄= 50	[11]
v₅	k₅·X₅·X₆- k_-5·X₇	k₅= 0.06	k_-5= 0.2	[11]
v₆	k₆·X₇- k_-6·X₈	k₆= 1	k_-6= 0.05	[11]
v₇	k₇·X₈- k_-7·X₅·X₉	k₇= 0.3	k_-7= 0.006	[11]
v₈	V₈·X₉/(K₈+ X₉)	V₈= 1	K₈= 100	[11]
v₉	k₉·X₉- k_-9·X₁₀	k₉= 1	k_-9= 0.03	[11]
v₁₀	k₁₀·X₉·X₁₁- k_-10·X₁₂	k₁₀= 0.214	k_-10= 5.25	Estimate
v₁₁	V₁₁·X₁₂·X₁₃/(K₁₁+ X₁₃)	V₁₁= 4	K₁₁= 64	[39]
v₁₂	V₁₂·X₁₄·X₁₅/[K₁₂·(1 + X₁₆/K₁₄) + X₁₅]	V₁₂= 3.5	K₁₂= 317	[14]
v₁₃	V₁₃·X₁₆/[K₁₃·(1 + X₁₇/K₁₅) + X₁₆]	V₁₃= 0.058	K₁₃= 2200	[12]
v₁₄	V₁₄·X₁₄·X₁₆/[K₁₄·(1 + X₁₅/K₁₂) + X₁₆]	V₁₄= 2.9	K₁₄= 317	[12]
v₁₅	V₁₅·X₁₇/[K₁₅·(1 + X₁₆/K₁₃) + X₁₇]	V₁₅= 0.058	K₁₅= 60	[12]
v₁₆	V₁₆·X₁₇·X₁₈/[K₁₆·(1 + X₁₉/K₁₈) + X₁₈]	V₁₆= 9.5	K₁₆= 1.46 × 10⁵	[12]
v₁₇	V₁₇·X₁₉/[K₁₇·(1 + X₂₀/K₁₉) + X₁₉]	V₁₇= 0.3	K₁₇= 160	[12]
v₁₈	V₁₈·X₁₇·X₁₉/[K₁₈·(1 + X₁₈/K₁₆) + X₁₉]	V₁₈= 16	K₁₈= 1.46 × 10⁵	[12]
v₁₉	V₁₉·X₂₀/[K₁₉·(1 + X₁₉/K₁₇) + X₂₀]	V₁₉= 0.27	K₁₉= 60	[12]

Wang et al. Theoretical Biology and Medical Modelling 2007 4:50 doi:10.1186/1742-4682-4-50