Table 4

Physiochemical parameters of EcoRII as predicted from the amino acid sequence alignments

Physicochemical parameter
Value

Number of amino acids:
404
Molecular Weight
45611
Theoretical PI
6.10
Total number of negatively charged residues (Asp+Glu)
52
Total number of positive residues (Arg+Lys)
43
Atomic composition:

     • Carbon(C)
2053
     • Hydrogen(H)
3205
     • Nitroge(N)
565
     • Oxygen(O)
393
     • Sulfur
10
Total number of atoms:
6426


Formula:
C2053H3205N565O593S10


Extinction coefficients:
47120(46870)


Estimated half-life(hours)

     • (mammalian reticulocytes, in vitro)
30 hour
     • (yeast, in vivo)
> 20 hours
     • (Escherichia coli, in vivo)
> 10 hours


Instability index:
45.04


Aliphatic index:
97.05


Grand average of hydropathicity (GRAVY)
-0.183

Wayengera et al. Theoretical Biology and Medical Modelling 2008 5:18   doi:10.1186/1742-4682-5-18