|
Model parameters |
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| Symbol |
Description |
Value |
Source |
|
|
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| μT |
natural healthy cell death rate |
0.02 day-1 |
[40–50 days] [19] |
| μP |
productively infected cell death rate |
0.5 day-1 |
[1–2 days] [20] |
| ST |
supply rate of target cells |
2 × 108 cells day-1 |
Estimated |
| ki |
viral strain infectivity |
varies |
Estimated |
| ε21 |
single-point mutation rate |
2.5 × 10-5 |
see Appendix |
| f |
probability of error free transcription |
0.37 |
Implied by ε21 |
Shiri and Welte Theoretical Biology and Medical Modelling 2008 5:25 doi:10.1186/1742-4682-5-25 |
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