Table 1
|
Maximum likelihood estimates of the parameters describing the clonal expansion, each corresponding to a QTL, and marker allele frequency, QTL allele frequency and marker-QTL linkage disequilibrium with 8 time points. Numbers in parentheses are the sampling errors of the estimates |
|||||
| n = 200 |
n = 400 |
||||
|
|
|
||||
| Para-meters |
True value |
H2 = 0.1 |
H2 = 0.4 |
H2 = 0.1 |
H2 = 0.4 |
|
|
|||||
| P |
0.5 |
0.48(0.023) |
0.49(0.021) |
0.49(0.014) |
0.50(0.012) |
| Q |
0.6 |
0.62(0.014) |
0.61(0.011) |
0.61(0.011) |
0.60(0.010) |
| D |
0.08 |
0.074(0.0067) |
0.075(0.003) |
0.079(0.004) |
0.079(0.004) |
 |
100 |
102.50(0.452) |
102.31(0.449) |
101.65(0.450) |
100.59(0.441) |
 |
0.1 |
0.097(0.00069) |
0.097(0.00062) |
0.098(0.00061) |
0.099(0.00012) |
 |
110 |
108.56(0.492) |
109.20(0.481) |
109.98(0.486) |
110.25(0.479) |
 |
0.15 |
0.147(0.0011) |
0.147(0.0011) |
0.149(0.0010) |
0.150(0.0007) |
 |
150 |
152.89(0.865) |
152.35(0.862) |
151.72(0.862) |
150.06(0.858) |
 |
0.2 |
0.209(0.0015) |
0.21(0.0014) |
0.21(0.0014) |
0.20(0.0011) |
 |
160 |
163.09(0.106) |
162.52(0.105) |
161.08(0.102) |
160.32(0.098) |
 |
0.25 |
0.244(0.0016) |
0.244(0.0016) |
0.248(0.0012) |
0.250(0.0011) |
 |
200 |
198.26(0.756) |
199.63(0.752) |
199.90(0.743) |
200.03(0.735) |
 |
0.25 |
0.247(0.0053) |
0.248(0.0050) |
0.248(0.0051) |
0.249(0.0046) |
 |
210 |
209.56(0.685) |
209.79(0.682) |
209.98(0.681) |
210.22(0.668) |
 |
0.30 |
0.311(0.002) |
0.311(0.001) |
0.308(0.001) |
0.302(0.0008) |
| ρ1 |
0.60 |
0.61(0.0078) |
0.61(0.0076) |
0.61(0.0071) |
0.61(0.0070) |
| ρ2 |
0.60 |
0.593(0.0022) |
0.595(0.0021) |
0.595(0.0021) |
0.598(0.0020) |
| σ1 |
1.31 |
1.322(0.0052) |
1.319(0.0045) |
||
| 0.538 |
0.539(0.0026) |
0.538(0.0019) |
|||
| σ2 |
1.31 |
1.322(0.0072) |
1.320(0.0056) |
||
| 0.53 |
0.53(0.0018) |
0.53(0.0011) |
|||
Das and Wu Theoretical Biology and Medical Modelling 2008 5:7 doi:10.1186/1742-4682-5-7 |
|||||