Ventricular Free Wall and Septal Elastance. Plots of RV free wall (Panel A), LV free wall (Panel B), and septal (Panel C) elastance. Open circles indicate outlet (pulmonic and aortic) valve opening, closed circles indicate outlet valve closure. Septal elastance bears a sharp peak coincident with RVF and LVF maximum elastance in control (black line). With IR-type (red line), LVF and septal elastance depict abnormal relaxation, and the peaks widen. With R-type (blue line), septal elastance peak is delayed, occurring after free wall elastance peaks, delaying aortic valve closure. With PN-type (green line), plots show signs of both effects with abnormal LVF and septal elastance downstroke, and delayed and widened septal elastance peak. In all LVDD cases, pulmonic valve opening is delayed. See text for details.
Luo et al. Theoretical Biology and Medical Modelling 2011 8:14 doi:10.1186/1742-4682-8-14