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A steady state analysis indicates that negative feedback regulation of PTP1B by Akt elicits bistability in insulin-stimulated GLUT4 translocation.

Giri L, Mutalik VK, Venkatesh KV.

Theor Biol Med Model. 2004 Aug 3;1:2.

PMID: 15291972 [PubMed - indexed for MEDLINE]

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Protein-tyrosine phosphatases PTP1B and syp are modulators of insulin-stimulated translocation of GLUT4 in transfected rat adipose cells.

Chen H, Wertheimer SJ, Lin CH, Katz SL, Amrein KE, Burn P, Quon MJ.

J Biol Chem. 1997 Mar 21;272(12):8026-31.

PMID: 9065475 [PubMed - indexed for MEDLINE]

A mathematical model of metabolic insulin signaling pathways.

Sedaghat AR, Sherman A, Quon MJ.

Am J Physiol Endocrinol Metab. 2002 Nov;283(5):E1084-101.

PMID: 12376338 [PubMed - indexed for MEDLINE]

Hyrtiosal, a PTP1B inhibitor from the marine sponge Hyrtios erectus, shows extensive cellular effects on PI3K/AKT activation, glucose transport, and TGFbeta/Smad2 signaling.

Sun T, Wang Q, Yu Z, Zhang Y, Guo Y, Chen K, Shen X, Jiang H.

Chembiochem. 2007 Jan 22;8(2):187-93.

PMID: 17183521 [PubMed - indexed for MEDLINE]

Insulin signaling diverges into Akt-dependent and -independent signals to regulate the recruitment/docking and the fusion of GLUT4 vesicles to the plasma membrane.

Gonzalez E, McGraw TE.

Mol Biol Cell. 2006 Oct;17(10):4484-93. Epub 2006 Aug 16.

PMID: 16914513 [PubMed - indexed for MEDLINE]

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Expression of constitutively active Akt/protein kinase B signals GLUT4 translocation in the absence of an intact actin cytoskeleton.

Eyster CA, Duggins QS, Olson AL.

J Biol Chem. 2005 May 6;280(18):17978-85. Epub 2005 Feb 28.

PMID: 15738003 [PubMed - indexed for MEDLINE]

Myosin 5a is an insulin-stimulated Akt2 (protein kinase Bbeta) substrate modulating GLUT4 vesicle translocation.

Yoshizaki T, Imamura T, Babendure JL, Lu JC, Sonoda N, Olefsky JM.

Mol Cell Biol. 2007 Jul;27(14):5172-83. Epub 2007 May 21.

PMID: 17515613 [PubMed - indexed for MEDLINE]

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Insulin and leptin induce Glut4 plasma membrane translocation and glucose uptake in a human neuronal cell line by a phosphatidylinositol 3-kinase- dependent mechanism.

Benomar Y, Naour N, Aubourg A, Bailleux V, Gertler A, Djiane J, Guerre-Millo M, Taouis M.

Endocrinology. 2006 May;147(5):2550-6. Epub 2006 Feb 23.

PMID: 16497805 [PubMed - indexed for MEDLINE]

The interaction of Akt with APPL1 is required for insulin-stimulated Glut4 translocation.

Saito T, Jones CC, Huang S, Czech MP, Pilch PF.

J Biol Chem. 2007 Nov 2;282(44):32280-7. Epub 2007 Sep 11.

PMID: 17848569 [PubMed - indexed for MEDLINE]

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Akt activation is required at a late stage of insulin-induced GLUT4 translocation to the plasma membrane.

van Dam EM, Govers R, James DE.

Mol Endocrinol. 2005 Apr;19(4):1067-77. Epub 2005 Jan 13.

PMID: 15650020 [PubMed - indexed for MEDLINE]

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Protein-tyrosine phosphatase 1B-deficient myocytes show increased insulin sensitivity and protection against tumor necrosis factor-alpha-induced insulin resistance.

Nieto-Vazquez I, Fernández-Veledo S, de Alvaro C, Rondinone CM, Valverde AM, Lorenzo M.

Diabetes. 2007 Feb;56(2):404-13.

PMID: 17259385 [PubMed - indexed for MEDLINE]

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Spatial and temporal regulation of GLUT4 translocation by flotillin-1 and caveolin-3 in skeletal muscle cells.

Fecchi K, Volonte D, Hezel MP, Schmeck K, Galbiati F.

FASEB J. 2006 Apr;20(6):705-7. Epub 2006 Feb 2.

PMID: 16455755 [PubMed - indexed for MEDLINE]

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Separation of insulin signaling into distinct GLUT4 translocation and activation steps.

Funaki M, Randhawa P, Janmey PA.

Mol Cell Biol. 2004 Sep;24(17):7567-77.

PMID: 15314166 [PubMed - indexed for MEDLINE]

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Role of Akt substrate of 160 kDa in insulin-stimulated and contraction-stimulated glucose transport.

Cartee GD, Wojtaszewski JF.

Appl Physiol Nutr Metab. 2007 Jun;32(3):557-66. Review.

PMID: 17510697 [PubMed - indexed for MEDLINE]

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Sphingomyelinase activates GLUT4 translocation via a cholesterol-dependent mechanism.

Liu P, Leffler BJ, Weeks LK, Chen G, Bouchard CM, Strawbridge AB, Elmendorf JS.

Am J Physiol Cell Physiol. 2004 Feb;286(2):C317-29. Epub 2003 Oct 1.

PMID: 14522816 [PubMed - indexed for MEDLINE]

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Coordinated regulation of insulin signaling by the protein tyrosine phosphatases PTP1B and TCPTP.

Galic S, Hauser C, Kahn BB, Haj FG, Neel BG, Tonks NK, Tiganis T.

Mol Cell Biol. 2005 Jan;25(2):819-29.

PMID: 15632081 [PubMed - indexed for MEDLINE]

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Corticosterone impairs insulin-stimulated translocation of GLUT4 in the rat hippocampus.

Piroli GG, Grillo CA, Reznikov LR, Adams S, McEwen BS, Charron MJ, Reagan LP.

Neuroendocrinology. 2007;85(2):71-80. Epub 2007 Apr 5.

PMID: 17426391 [PubMed - indexed for MEDLINE]

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The Rab GTPase-activating protein AS160 integrates Akt, protein kinase C, and AMP-activated protein kinase signals regulating GLUT4 traffic.

Thong FS, Bilan PJ, Klip A.

Diabetes. 2007 Feb;56(2):414-23.

PMID: 17259386 [PubMed - indexed for MEDLINE]

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Disruption of microtubules ablates the specificity of insulin signaling to GLUT4 translocation in 3T3-L1 adipocytes.

Huang J, Imamura T, Babendure JL, Lu JC, Olefsky JM.

J Biol Chem. 2005 Dec 23;280(51):42300-6. Epub 2005 Oct 20.

PMID: 16239226 [PubMed - indexed for MEDLINE]

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Identification of 80K-H as a protein involved in GLUT4 vesicle trafficking.

Hodgkinson CP, Mander A, Sale GJ.

Biochem J. 2005 Jun 15;388(Pt 3):785-93.

PMID: 15707389 [PubMed - indexed for MEDLINE]

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