Your browser version may not work well with NCBI's Web applications. More information here...

Recent Activity

Items 1 - 20 of 101
of 6Next
1:

Simulating non-small cell lung cancer with a multiscale agent-based model.

Wang Z, Zhang L, Sagotsky J, Deisboeck TS.

Theor Biol Med Model. 2007 Dec 21;4:50.

PMID: 18154660 [PubMed - indexed for MEDLINE]

2:

The effects of cetuximab alone and in combination with radiation and/or chemotherapy in lung cancer.

Raben D, Helfrich B, Chan DC, Ciardiello F, Zhao L, Franklin W, Barón AE, Zeng C, Johnson TK, Bunn PA Jr.

Clin Cancer Res. 2005 Jan 15;11(2 Pt 1):795-805.

PMID: 15701870 [PubMed - indexed for MEDLINE]

3:

Epidermal growth factor ligand/receptor loop and downstream signaling activation pattern in completely resected nonsmall cell lung cancer.

Volante M, Saviozzi S, Rapa I, Ceppi P, Cappia S, Calogero R, Novello S, Borasio P, Papotti M, Scagliotti GV.

Cancer. 2007 Sep 15;110(6):1321-8.

PMID: 17647268 [PubMed - indexed for MEDLINE]

4:

Simulating the impact of a molecular 'decision-process' on cellular phenotype and multicellular patterns in brain tumors.

Athale C, Mansury Y, Deisboeck TS.

J Theor Biol. 2005 Apr 21;233(4):469-81. Epub 2004 Nov 30. Erratum in: J Theor Biol. 2006 Apr 21;239(4):516-7.

PMID: 15748909 [PubMed - indexed for MEDLINE]

5:

A multiscale computational approach to dissect early events in the Erb family receptor mediated activation, differential signaling, and relevance to oncogenic transformations.

Liu Y, Purvis J, Shih A, Weinstein J, Agrawal N, Radhakrishnan R.

Ann Biomed Eng. 2007 Jun;35(6):1012-25. Epub 2007 Feb 2.

PMID: 17273938 [PubMed - indexed for MEDLINE]

6:

Expression of epidermal growth factor receptor (EGFR) and downstream-activated peptides in surgically excised non-small-cell lung cancer (NSCLC).

Mukohara T, Kudoh S, Yamauchi S, Kimura T, Yoshimura N, Kanazawa H, Hirata K, Wanibuchi H, Fukushima S, Inoue K, Yoshikawa J.

Lung Cancer. 2003 Aug;41(2):123-30.

PMID: 12871775 [PubMed - indexed for MEDLINE]

7:

Development of a three-dimensional multiscale agent-based tumor model: simulating gene-protein interaction profiles, cell phenotypes and multicellular patterns in brain cancer.

Zhang L, Athale CA, Deisboeck TS.

J Theor Biol. 2007 Jan 7;244(1):96-107. Epub 2006 Jul 27.

PMID: 16949103 [PubMed - indexed for MEDLINE]

8:

Matuzumab and cetuximab activate the epidermal growth factor receptor but fail to trigger downstream signaling by Akt or Erk.

Yoshida T, Okamoto I, Okabe T, Iwasa T, Satoh T, Nishio K, Fukuoka M, Nakagawa K.

Int J Cancer. 2008 Apr 1;122(7):1530-8.

PMID: 18033688 [PubMed - indexed for MEDLINE]

9:

Epidermal growth factor and hypoxia-induced expression of CXC chemokine receptor 4 on non-small cell lung cancer cells is regulated by the phosphatidylinositol 3-kinase/PTEN/AKT/mammalian target of rapamycin signaling pathway and activation of hypoxia inducible factor-1alpha.

Phillips RJ, Mestas J, Gharaee-Kermani M, Burdick MD, Sica A, Belperio JA, Keane MP, Strieter RM.

J Biol Chem. 2005 Jun 10;280(23):22473-81. Epub 2005 Mar 31.

PMID: 15802268 [PubMed - indexed for MEDLINE]

10:

Antitumor activity of the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor gefitinib (ZD1839, Iressa) in non-small cell lung cancer cell lines correlates with gene copy number and EGFR mutations but not EGFR protein levels.

Helfrich BA, Raben D, Varella-Garcia M, Gustafson D, Chan DC, Bemis L, Coldren C, Barón A, Zeng C, Franklin WA, Hirsch FR, Gazdar A, Minna J, Bunn PA Jr.

Clin Cancer Res. 2006 Dec 1;12(23):7117-25.

PMID: 17145836 [PubMed - indexed for MEDLINE]

11:

Epidermal growth factor receptor (EGFR) downstream molecules as response predictive markers for gefitinib (Iressa, ZD1839) in chemotherapy-resistant non-small cell lung cancer.

Han SW, Hwang PG, Chung DH, Kim DW, Im SA, Kim YT, Kim TY, Heo DS, Bang YJ, Kim NK.

Int J Cancer. 2005 Jan 1;113(1):109-15.

PMID: 15386420 [PubMed - indexed for MEDLINE]

12:

Inhibition of epidermal growth factor receptor signaling elevates 15-hydroxyprostaglandin dehydrogenase in non-small-cell lung cancer.

Yang L, Amann JM, Kikuchi T, Porta R, Guix M, Gonzalez A, Park KH, Billheimer D, Arteaga CL, Tai HH, DuBois R, Carbone DP, Johnson DH.

Cancer Res. 2007 Jun 15;67(12):5587-93.

PMID: 17575121 [PubMed - indexed for MEDLINE]

13:

The effects of EGF-receptor density on multiscale tumor growth patterns.

Athale CA, Deisboeck TS.

J Theor Biol. 2006 Feb 21;238(4):771-9. Epub 2005 Aug 26.

PMID: 16126230 [PubMed - indexed for MEDLINE]

14:

Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer.

Cappuzzo F, Hirsch FR, Rossi E, Bartolini S, Ceresoli GL, Bemis L, Haney J, Witta S, Danenberg K, Domenichini I, Ludovini V, Magrini E, Gregorc V, Doglioni C, Sidoni A, Tonato M, Franklin WA, Crino L, Bunn PA Jr, Varella-Garcia M.

J Natl Cancer Inst. 2005 May 4;97(9):643-55.

PMID: 15870435 [PubMed - indexed for MEDLINE]

16:

An update of the mechanisms of resistance to EGFR-tyrosine kinase inhibitors in breast cancer: Gefitinib (Iressa) -induced changes in the expression and nucleo-cytoplasmic trafficking of HER-ligands (Review).

Ferrer-Soler L, Vazquez-Martin A, Brunet J, Menendez JA, De Llorens R, Colomer R.

Int J Mol Med. 2007 Jul;20(1):3-10. Review.

PMID: 17549382 [PubMed - indexed for MEDLINE]

17:

Gefitinib-induced killing of NSCLC cell lines expressing mutant EGFR requires BIM and can be enhanced by BH3 mimetics.

Cragg MS, Kuroda J, Puthalakath H, Huang DC, Strasser A.

PLoS Med. 2007 Oct;4(10):1681-89; discussion 1690.

PMID: 17973573 [PubMed - indexed for MEDLINE]

18:

Modeling T cell antigen discrimination based on feedback control of digital ERK responses.

Altan-Bonnet G, Germain RN.

PLoS Biol. 2005 Nov;3(11):e356. Epub 2005 Oct 25.

PMID: 16231973 [PubMed - indexed for MEDLINE]

19:

Parsing ERK activation reveals quantitatively equivalent contributions from epidermal growth factor receptor and HER2 in human mammary epithelial cells.

Hendriks BS, Orr G, Wells A, Wiley HS, Lauffenburger DA.

J Biol Chem. 2005 Feb 18;280(7):6157-69. Epub 2004 Nov 29.

PMID: 15572377 [PubMed - indexed for MEDLINE]

20:

Activated epidermal growth factor receptor-Stat-3 signaling promotes tumor survival in vivo in non-small cell lung cancer.

Haura EB, Zheng Z, Song L, Cantor A, Bepler G.

Clin Cancer Res. 2005 Dec 1;11(23):8288-94.

PMID: 16322287 [PubMed - indexed for MEDLINE]

Items 1 - 20 of 101
of 6Next